Intramolecular aliphatic C–H amination reactions are greatly sought-after for the synthesis of N-containing heterocycles, but current methods require the use of highly activated nitrogen sources. Now, ...

The strained cyclic amides known as β-lac­tams have shown up in the skeletons of many medicinally important molecules, including the antibiotic penicillin and the cardiac drug Zetia (ezetimibe).

Amines are an important class of organic compounds. Students might be aware that adrenaline and ephedrine, which contain secondary amino groups, are used to increase blood pressure. Novocain which is ...