Tubulin acts as a master regulator, preventing Tau and alpha-synuclein from forming toxic clumps in Alzheimer's and Parkinson's.

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils. Parkinson's ...

A new study has revealed how the mutated proteins that are a hallmark of Parkinson’s disease spread and aggregate in the brain. The finding opens the door to developing a way of halting the disease’s ...

Alpha-synuclein aggregation is a hallmark of Parkinson's disease and other synucleinopathies. It is a dynamic process in which the protein self-assembles to form oligomers that eventually develop ...

People with Parkinson’s disease may also experience cognitive changes and struggle with day-to-day activities. Research is ongoing about the specific components of Parkinson’s disease and what actions ...

Could synucleinopathies start in the kidneys? In the January 23 Nature Neuroscience, scientists led by Zhentao Zhang at Wuhan University, China, report that, in people with Parkinson’s and Lewy body ...

A newly identified receptor rolls out the red carpet for α-synuclein fibrils, ushering them inside neurons and fast-tracking their spread, according to research from Fudan University, Shanghai. In the ...