Scientists have deciphered the molecular structure of a widely prescribed antipsychotic docked in its key receptor. They are hopeful that this discovery may hold secrets to designing better treatments ...

Philadelphia, PA, March 11, 2013 – Antipsychotic administration in the elderly is associated with an increased risk for cerebrovascular accident, more commonly known as stroke; a new study published ...

Antipsychotic drugs - which transformed mental health care following their chance discovery in the mid-20th Century - may finally be poised for a long-overdue makeover incorporating structure-based ...

Antipsychotic medicines are a key part of the pharmacological treatment of schizophrenia. Although they provide therapeutic ...

Many schizophrenic and depressed patients experience weight gain and type 2 diabetes in their quests for the life-changing benefits of a major class of antipsychotic drugs. Now researchers may know ...

An investigational, phase II study published in the scientific journal Nature Medicine demonstrates that for the first time in humans a drug that acts on certain proteins in the brain called mGlu2/3 ...

Irvine, Calif., July 6, 2016 -- Since their development in the 1950s, antipsychotic drugs have been widely used to treat psychoses and neuropsychiatric disorders like schizophrenia. A debilitating ...

Management of adverse events is a major concern of clinicians who use antipsychotic drugs. The incidence of motor side effects is dose dependent. Atypical antipsychotic drugs are less likely to induce ...

New University of Pittsburgh research points to a potential approach to reducing the risk of diabetes associated with widely prescribed antipsychotic medications. The study, including experiments in ...

Credit: Thinkstock. Antipsychotics used to treat disorders such as schizophrenia, bipolar disorder, and other psychoses mainly involve D2 receptor antagonism and some newer agents target D4 antagonism ...

Neumora Therapeutics, Inc. has announced the initiation of a Phase 1 study for NMRA-861, a potent and selective positive allosteric modulator of the M4 muscarinic receptor, aimed at treating ...

Expert Rev Clin Pharmacol. 2008;1(6):791-802. Expert Rev Clin Pharmacol. 2008;1(6):791-802. © 2008 Expert Reviews Ltd. Cite this: Possible Dose-Side Effect ...