Researchers from the Structural Biology Brussels group at Vrije Universiteit Brussel (VUB) have uncovered a significant mechanism that may contribute to amyotrophic lateral sclerosis (ALS), a disease ...

University of South Carolina scientists are exploring ways to make nerve regeneration happen faster and more successfully. "The important thing is that we identified the protein that drives that ...

Tumors that produce more stress granules are more likely to metastasize, according to researchers. The results suggest that drugs to inhibit the formation of these structures might rein in cancer ...

St. Jude Children's Research Hospital scientists are studying the processes that enable cells to respond and adapt to environmental stress, many of which are also associated with neurodegenerative ...

Minimally disruptive genetic code expansion enables faithful, site-specific labeling of G3BP1 and TDP-43, revealing native stress granule dynamics and ALS-linked protein behavior in live cells.

When ubiquitin-specific peptidase 10 (USP10) and Caprin-1 bind to the nuclear transport factor 2-like (NTF2L) domain of Ras GTPase-activating protein-binding protein 1 (G3BP1), Caprin-1 facilitates the ...

Under adverse conditions, healthy cells and tumor cells alike form stress granules, clumps of mRNA and protein that are stashed away for later use. Although it has been known that stress granules can ...