Sickle cell disease refers to a group of genetic disorders that affect hemoglobin. Red blood cells contain hemoglobin, which is a molecule that delivers oxygen to the body’s tissues. In sickle cell ...
Sickle cell beta-thalassemia refers to an inherited condition that impacts hemoglobin. People with the condition have different changes in each copy of their hemoglobin gene. One causes red blood ...
Myeloablative allogeneic hematopoietic stem-cell transplantation is curative in children with sickle cell disease, but in adults the procedure is unduly toxic. Graft rejection and graft-versus-host ...
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