Inhibiting an immune signaling protein called TLR7 may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led ...
The study showed that introducing the TLR7 variant in an animal model led to the development of autoimmune symptoms and potential development of systemic lupus erythematosus (SLE). A new report ...
FURTHER: A global study to evaluate furmonertinib in patients with EGFR mutant NSCLC including uncommon EGFR mutations (FURMO-002). Background: Immune checkpoint inhibitors (ICIs) relieve ...
Effect of cancer vaccine formulation on synergy with anti-CTLA-4 and anti-PD-L1 checkpoint blockade therapy of cancer. Background: Toll-like receptors (TLRs) are proteins in the innate immune system ...
A study published in Nature on April 27, 2022, provides evidence indicating that the currently incurable chronic autoimmune disease, systemic lupus erythematosus (SLE), is caused by gain-of-function ...
Results from the Phase II WILLOW trial show that enpatoran achieved a statistically significant dose-response and clinically meaningful reduction in disease activity in cutaneous and systemic lupus ...
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