Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...
Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.
The canonical Wnt signaling pathway. The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz ...
The secreted WNT proteins activate two distinct signaling pathways: the canonical WNT/β-catenin pathway and a WNT/Ca 2+ pathway that interferes with the canonical pathway. In the May 16 Nature, ...
Spiperone, ionomycin, thapsigargin (Tg), pindolol, UH-301, WAY100635, 8-OH-DPAT, SB-269970, NAN-190, SB-204741, Ketaserin, Clozapine, DTG (1,3-di-o-tolylguanidine) and GF109203X were purchased from ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results