Alder–Reilly anomaly Alder–Reilly anomaly, or Alder anomaly, is an inherited abnormality of white blood cells associated with mucopolysaccharidosis.

Alder-Reilly's anomaly is characterized by abnormal granulation of almost all neutrophilic granulocytes. Aberrant or increased granulation may additionally occur in eosinophils, basophils, lymphocytes and …

Dec 29, 2025 · Alder-Reilly anomaly is a rare, inherited genetic condition characterized by the presence of large, abnormally staining granules in the cytoplasm of white blood cells (leukocytes), particularly …

On the other hand, the Alder-Reilly anomaly was identified on neutrophils from MPS I, IV, and VI patients [45, 52-55], representing a potential finding for this LSD group.

Mar 11, 2013 · Dense granules, resembling toxic granulation in neutrophils, are seen in all leukocytes. The Alder-Reilly anomaly is seen in the mucopolysaccharidoses. The most characteristic finding is …

Granulocytes show metachromatic and darkly staining inclusions (Alder-Reilly bodies) containing partially digested mucopolysaccharides that resemble toxic granulation but are permanent (non …

Jul 28, 2025 · Here, we describe a 7-year-old boy diagnosed as Maroteaux-Lamy syndrome, showing typical skeletal abnormalities and facial dysmorphism, as well as the presence of characteristic Alder …