UniProt - SlideServe
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Using UniProt for protein structure function analysis
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Brianna Bibel on Instagram: "Software tools and databases for working with proteins Blog: https://thebumblingbiochemist.com/365-days-of-science/proteintools/ PDF: https://drive.google.com/file/d/1G7OVk6G_AiYPJugIw_DHX-JxtIvLhOBB/view?usp=drive_link YouTube: https://youtu.be/encoJwuD6Pk * UniProt - basics (functions, length, sequence(s), isoforms, structures, interactions, etc. - lots of links to more detailed databases for each) https://www.uniprot.org/ * more about it on my blog: https://bit.ly
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Brianna Bibel on Instagram: "Interpreting AlphaFold predictions and confidence indicators https://youtu.be/i_aou7FRySw AlphaFold is sometimes easier to use than to interpret, so here's a quick guide... https://thebumblingbiochemist.com/365-days-of-science/interpreting-alphafold-predictions/ AlphaFold uses AI to, based on knowledge gained about the relationship between protein sequences and their corresponding structures (thanks to lots of work by structural biologists!), predict the structure of
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Brianna Bibel on Instagram: "Uniprot vs. the PDB: Understanding their entries and differences Bottom line: * Each entry in Uniprot corresponds to a protein (chain) * Each entry in the PDB (Protein DataBank) corresponds to a structural model which can contain part of a protein chain, a whole protein chain, multiple protein chains, proteins bound to things, DNA, RNA, etc.) Each UniProt entry can be associated with multiple PDB entries (and you can even link out to them directly from UniProt) and e
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